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While under pathological conditions, oxygen reacts with excess labile iron and generates ROS that attacks lipid membrane, implicated in lipid peroxidation (Han et al., 2020)

Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress. Frontiers in endocrinology vol

Both overuse of antibiotics and poor nutrition (including a low-fiber diet) can reduce the levels of SCFAs in the colon, because both reduce the healthy fermentation that normally occurs due to the interactions of fiber, food, and the microbiome

However, the cold shock and alterations in atmospheric oxygen seriously led to biochemical, biophysical, ultrastructural, molecular, and functional alterations (57)